The role of inflammatory miRNA-mRNA interactions in PBMCs of colorectal cancer and obesity patients
nflammation is a critical hallmark in obesity and colorectal cancer (CRC). This study aimed to investigate effective microRNA (miRNA)–messenger RNA (mRNA) interactions on inflammatory networks involved in obesity and CRC
Evaluation of the performance of osteoporosis/fracture screening models to identify high-risk women for osteoporosis: Bushehr elderly health (BEH) program
This study aimed to evaluate the performance of valid risk assessment models developed for osteoporosis/ fracture screening to identify women in need of bone density measurement in a population of Iranian elderly women
Vascular Endothelial Growth Factor Genetic Variant is Associated with In-Stent Restenosis after Percutaneous Coronary Intervention
The vascular endothelial growth factor (VEGF) gene can have an inhibitory effect on ISR development. Accordingly, in the present study, we investigated the role of -2549 VEGF (insertion/deletion [I/D]) variants in ISR formation.
Role of genetic polymorphisms in recurrent aphthous stomatitis: A systematic review and meta-analysis
Recurrent aphthous stomatitis (RAS) is one of the most common oral ulcerative diseases with unknown etiology. Identifying the genetic markers can improve medical care and prevention of RAS. Genetics variants inflammatory agents are associated with the risk of RAS. Thus, this meta-analysis aimed to investigate the genetic polymorphisms in RAS. Electronic literature search was carried out on Scopus, PubMed, and Web of Science (WOS).
Adenosine deaminase gene variant in diabetes and obesity
Personal medicine is a new notion for individualizing treatment in the future. Studying pathogenic markers including genetic variants would be beneficial in better diagnosis and management of complex diseases such as diabetes and obesity. Adenosine deaminase (ADA) is a purine metabolic enzyme and modulates insulin activity in various tissues through several different mechanisms. Increased ADA activity is associated with decreased glucose uptake.
Early and delayed puberty among Iranian children with obesity
This study aimed to investigate the prevalence and risk factors of the puberty disturbances among children with obesity in Tehran, Iran. Methods: This study was performed as a cross-sectional
The vitamin D receptor gene variants, ApaI, TaqI, BsmI, and FokI in diabetic foot ulcer and their association with oxidative stress
It has been postulated that vitamin D may influence insulin activity, which can predispose individuals to develop type 2 diabetes
The importance of regulatory pathway mediated by Circ0001955 in colorectal cancer
we decided to design this study to evaluate the expression levels of circ
Study of the frequency and clinical features of maturity-onset diabetes in the young in the pediatric and adolescent diabetes population in Iran
This study was done to investigate the prevalence of MODY subtypes and patients' clinical characteristics
Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity
This study aimed to examine miRNAs binding sites variants on inflammatory genes identified using bioinformatics and systematic approach on clinical samples that were collected from CRC patients and controls