About Metabolic Disorders Research Center

The Metabolic Disorders Research Center (MDRC) is one of the 13 research centers that form the subgroups of the Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences. This center was established in 2012 to provide better conditions for patients with metabolic disorders. The center's mission is to help diagnose hereditary metabolic diseases, followed by treatment and prevention of these diseases, and research on their prevalence in Iran, as well as metabolomic research. It was established in the field of hereditary metabolic and endocrine diseases. The center is committed to creating a multipurpose center for diagnosis, consultation, and training for patients and doctors. For more information about the center, you can refer to the center at a glance section of the main page.

 

Field of activity

Molecular-cellular studies in endocrine diseases including diabetes, obesity, osteoporosis, and hyperlipidemia. Finding mutations of rare endocrine diseases in the Iranian population and studying the genetics of glandular cancers (including thyroid) at the cellular and molecular levels.

 

General objectives

Research to improve health status, diagnosis, and appropriate treatment of hereditary metabolic diseases

Research to achieve equal treatment outcomes for people with different socioeconomic status

National registry of metabolic diseases for treatment planning

Research to develop suggested strategies for better management of these diseases, including:

- Nutrition and diet therapy

- Drug therapy

 

Research and clinical goals

1- Clinical research area

Research on methods for diagnosing metabolic diseases and reporting mostly rare cases.

Investigation into the diagnosis of new disorders using advanced equipment

Clinical research on patients referred to the clinic, nutrition unit, and diet therapy for metabolic patients

 

2- Basic science research area

Metabolomics research

Enzyme studies

Cellular-molecular studies

Launching genetic and biochemical diagnostic tests of the metabolic panel for diagnosis and treatment

 

3- Population research area

Investigation of prevalence and incidence based on:

Study on software methods for diagnosing metabolic diseases and Big Data analysis

Patients referred to the clinic

Results from the Registry

Results from international collaborations on data from samples

 

Educational Objectives

1- Holding workshops and seminars on

Treatment of metabolic diseases

Biochemical, molecular, and genetic basis of metabolic diseases

Holding workshops on advanced laboratory methods for diagnosis and follow-up of metabolic diseases

2- Admission and training of PhD, postdoctoral, and research fellow students, masters, residents, and fellowship theses